ANTI-HUMAN IGG4
- Product NameANTI-HUMAN IGG4
- CAS
- CBNumberCB5222694
- MW0
- MDL NumberMFCD00164659
- MOL FileMol file
Chemical Properties
storage temp. | -20°C |
ANTI-HUMAN IGG4 Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
Sigma-Aldrich I9888 | 0.2mL | $205 | Monoclonal Anti-Human IgG4 (pFc′ specific) antibody produced in mouse clone HP-6023, ascites fluid |
Buy |
American Custom Chemicals Corporation ATB0011173 | 5MG | $503.11 | ANTI-HUMAN IGG4 95.00% |
Buy |
ANTI-HUMAN IGG4 Chemical Properties,Usage,Production
Uses
The IUIS/WHO2 study singled out this monoclonal antibody as one of the most widely applicable IgG4 specific monoclonal antibodies. Monoclonal Anti-Human IgG4 may be used for the identification of the IgG4 subclass by various immunoassays including: ELISA, Imprint Immunofixation (IIF), Immunofluorometric Assay (IFMA), Hemagglutination (HA), Hemagglutination Inhibition (HAI), Particle Counting Immunoassay (PACIA), and detection of cytoplasmic IgG.Uses
Monoclonal Anti-Human IgG4 (pFc′ specific) antibody can be used for immunoblotting and Indirect Immunoperoxidase Assay.General Description
IgG4 (Immunoglobulin G4) is produced by T helper 2 cytokines. Unlike other immunoglobulin G is rare and constitutes to only 3-4 percent of the total IgG in the serum.Biochem/physiol Actions
IgG4 (Immunoglobulin G4) antibody has reduced affinity for C1q (first component of complement q) and hence its anti-inflammatory activity differing from that of the other IgG subclasses. IgG4 antibodies are known to actively interchange Fab arms with another molecule, resulting in recombined antibodies with two different binding specificities. This exchange is considered as an important biological mechanism that contributes to its anti-inflammatory activity. IgG4 antibodies are normally noninflammatory, but autoreactive IgG4 antibodies are known to be associated with Immunoglobulin G4 (IgG4)-related disease (IgG4-RD), characterized by infiltrating lymphoplasmacytic cells and elevated serum IgG4. Increased levels of IgG4 is observed in atopic dermatitis, parasitic diseases, pemphigus vulgaris and pemphigus foliaceus.Preparation Products And Raw materials
ANTI-HUMAN IGG4 Suppliers
Global(13)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
-- | United States | 6825 | 87 | ||
-- | Switzerland | 6913 | 91 | ||
-- | United States | 540 | 50 | ||
-- | cs@piercenet.com | United States | 966 | 82 | |
-- | info@karlan.com | United States | 420 | 51 | |
-- | reag-info@gms.kanto.co.jp | Japan | 6762 | 74 | |
-- | United States | 1183 | 86 | ||
-- | info@cortex-biochem.com | United States | 1557 | 77 | |
-- | caltag@caltag.com | United States | 1313 | 63 | |
-- | jaeger@biotrend.com | Germany | 6115 | 76 |
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