Uses
Scorpion venom from
Leiurus quinquestriatus (north Africa) has been used to monitor stimulation levels and to test its effect on receptor responses in slowly adapting (SA) abdominal stretch receptor neurons. It has also been used to test its effect on γ-aminobutyric acid (GABA) release?in the isolated synapse of crayfish.
General Description
Note: This venom is distinguishable from
L.q. hebraeus (V1755) electrophoretically. This may be due in part to the presence of ToxinV in the North African venom.
Biochem/physiol Actions
Scorpion venom from Leiurus quinquestriatus has high levels of zinc and manganese. It elicits harmful effects and is reported to induce cytotoxicity and enhance apoptosis in cancer cell lines.