Description
5S(6R)-EET is an oxylipin. It depolarizes transepithelial voltage in isolated rabbit renal cortical collecting duct when applied to the luminal side at a concentration of 1 µM.1 In solution, 5(6)-EET degrades into 5,6-DiHET and 5(6)-δ-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS.2WARNING This product is not for human or veterinary use.
References
[1] Y SAKAIRI. 5,6-EET inhibits ion transport in collecting duct by stimulating endogenous prostaglandin synthesis.[J]. American Journal of Physiology, 1995, 268 5 Pt 2: F931-9. DOI:
10.1152/ajprenal.1995.268.5.f931[2] MAMUNUR RASHID . Identification of the binding sites and selectivity of sarpogrelate, a novel 5-HT2 antagonist, to human 5-HT2A, 5-HT2B and 5-HT2C receptor subtypes by molecular modeling[J]. Life sciences, 2003, 73 2: Pages 193-207. DOI:
10.1016/s0024-3205(03)00227-3
