pleurosine

Description

One of the Vinca alkaloids, this complex base occurs in V. rosea L. It may be purified by recrystallization from MeOH when it forms colourless blades. It is 1aevorotatory with [o:)fi6 - 61 ° (c 1.0, CHC13) and gives an ultraviolet spectrum having two absorption maxima at 267 and 308 ffiP.. The structure is that of leurosine Nb-oxide.

References

Svoboda ct al., 1. Pharrn. Sci., 51, 518 (1962)