Description
LY 81067 is a new anticonvulsive agent.
Uses
LY81067, a diaryltriazine, effectively protects against Pentylenetetrazole- and Picrotoxin-induced convulsions in mice. LY81067 exerts its anticonvulsant effects by binding to or near Picrotoxin (HY-101391) binding sites[1].
References
[1] D T Wong,et al. Enhanced binding of radioligands to receptors of gamma-aminobutyric acid and benzodiazepine by a new anticonvulsive agent, LY81067. Life Sci. 1983 Sep 5;33(10):917-23. DOI:
10.1016/0024-3205(83)90747-6
