N-(2,3-dihydro-1H-inden-2-yl)-2-(pyridin-3-yl)quinazolin-4-amine Chemical Properties,Usage,Production
Description
JZ-4109 is a β-Glucocerebrosidase modulator which promotes dimerization of β-glucocerebrosidase and reveals an allosteric binding site, thereby stabilizing wild-type and N370S mutant GCase and increasing GCase abundance in patient-derived fibroblast cells.