Chemical Properties
2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE is white to off-white powder
Uses
2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE is used for solid-phase peptide synthesis with FMOC strategy
Preparation
Preparation by Friedel–Crafts acylation of resorcinol dimethyl ether with p-hydroxybenzoic acid,
? in the presence of zinc chloride and phosphorous oxychloride at 60–65° for 1.5 h (71%) or in nitrobenzene at 60° for 2–3 h;
? in the presence of polyphosphoric acid.
reaction suitability
reagent type: cross-linking reagent