1,3-Diarachidonoyl Glycerol

Uses

1,3-Diarachidonoyl glycerol (DG(20:4/0:0/20:4)) is a compound that is being studied for its selective cell killing mechanism, and it has a selective killing effect on cells transformed by the E1A gene of adenovirus type 12. Its killing effect is attributed to lipid peroxidation, and its structural characteristics are crucial to the specificity of this cytotoxicity, which ultimately exerts cytotoxic effects by destroying the cell membrane.

References

[1] Mechanism of selective killing by dilinoleoylglycerol of cells transformed by the E1A gene of adenovirus type 12 PMID:2529026