Uses
C3 Peptide P16, is a 16 amino acid synthetic peptide derived from human C3d, a fragment generated in trypsin-cleaved C3. C3 Peptide P16 enhances in vitro phosphorylation of pp105 and pp100, a cellular component presenting in the human B lymphoma cells[1][2].
References
[1] Sachdeva R, et al. DING proteins from phylogenetically different species share high degrees of sequence and structure homology and block transcription of HIV-1 LTR promoter. PLoS One. 2013 Aug 6;8(8):e69623. DOI:
10.1371/journal.pone.0069623[2] Frade R, et al. A 16 amino acid synthetic peptide derived from human C3d triggers proliferation and specific tyrosine phosphorylation of transformed CR2-positive human lymphocytes and of normal resting B lymphocytes. Biochem Biophys Res Commun. 1992 Oct 30;188(2):833-42. DOI:
10.1016/0006-291x(92)91132-a[3] Lyamani F, et al. A 16 amino-acid synthetic peptide, derived from human C3d, carries regulatory activity on in vitro phosphorylation of a cellular component of the human B lymphoma cells, Raji. Biochem Biophys Res Commun. 1991 Mar 29;175(3):823-30. DOI:
10.1016/0006-291x(91)91639-t