GATX2

Uses

GaTx2 is a seletive and a high affinity inhibitor of ClC-2 channels with a voltage-dependent apparentKDof ～20 pM. GaTx2 is a peptide toxin inhibitorfromLeiurus quinquestriatus hebraeusvenom. GaTx2 is useful in determining the role and the membrane localization of ClC-2 in specific cell types[1].

References

[1] Christopher H Thompson, et al. Isolation and characterization of a high affinity peptide inhibitor of ClC-2 chloride channels.J Biol Chem DOI:10.1074/jbc.M109.031724