Dnp-PLALWAR (trifluoroacetate salt)

Description

Dnp-PLALWAR is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-8.1 The activity of MMP-1 and MMP-8 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis that removes the N-terminal dinitrophenol (Dnp) group.WARNING This product is not for human or veterinary use.

References

[1] SARAH NETZEL-ARNETT . Continuously recording fluorescent assays optimized for five human matrix metalloproteinases[J]. Analytical biochemistry, 1991, 195 1: Pages 86-92. DOI: 10.1016/0003-2697(91)90299-9