Uses
sphingomyelinase is a fluid that can enhance the skin’s moistureretention properties.
Uses
Sphingomyelinase from
Staphylococcus aureus has been used to:
- induce neurotoxicity in rat cortical cultures to study the protective effects of minocycline
- determine the concentration of sphingomyelin from serum samples
- enhance sphingomyelinase activity to study PARK9-mediated exosome biogenesis
Uses
Sphingomyelinase from
Bacillus cereus has been used:
- in the measurement of membrane capacitance in brain slices
- for testing and confirming its silkworm-killing activity
- in enzyme activity assay and for elucidating its effect on hydrolysis of sphingomyelin in complex lipid mixtures
General Description
Sphingomyelinase from
Bacillus cereus (Bc-Smase) is a Mg
2+-containing metalloenzyme.
Bacillus cereus sphingomyelinase induces hemolysis of sheep erythrocytes.
Biochem/physiol Actions
Initiates the formation of sphingomyelin-based second messengers. Activates MAPK (mitogen-activated protein kinase) and SAPKs (stress-activated protein kinases); generates ceramide from sphingomyelin.
