1-Propanone, 1-(3-chloro-2-hydroxyphenyl)-

Preparation

Obtained by Fries rearrangement of o-chlorophenyl propionate
with aluminium chloride at 110° for 2 h (35%)
with titanium tetrachloride at 100° for 7 h (17%)
with zirconium chloride in o-dichlorobenzene over 1 h at 120°
Also obtained by isomerization of 3-chloro-4-hydroxypropiophenone with aluminium chloride at 180–200° for 1 h (24%)
Also obtained by tert-butyl group elimination of 5-tert-butyl-3-chloro-2- hydroxypropiophenone with aluminium chloride at 190° for 15 min (80%).