Drug interactions
Potentially hazardous interactions with other drugs
Antibacterials: possible increased risk of ventricular
arrhythmias with delamanid.
Antifungals: possible increased risk of toxicity with
itraconazole.
Antipsychotics: avoid with clozapine (increased risk
of agranulocytosis).
Metabolism
Vindesine is metabolised by cytochrome P450 (in the CYP 3A subfamily). Elimination is primarily via the biliary route, but 13
% is excreted in urine in 24 hours.
