Exendin-4 (Acetate)
- Product NameExendin-4 (Acetate)
- CAS914454-01-6
- CBNumberCB43048652
- MFC186H285N50O62RS
- MW4245.62
- MOL File914454-01-6.mol
Chemical Properties
storage temp. | Store at -20°C |
solubility | PBS (pH 7.2): 3 mg/ml |
form | A crystalline solid |
Exendin-4 (Acetate) Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
Cayman Chemical 11096 | 500μg | $101 | Exendin-4 (acetate) ≥95% |
Buy |
Cayman Chemical 11096 | 1mg | $162 | Exendin-4 (acetate) ≥95% |
Buy |
Cayman Chemical 11096 | 5mg | $379 | Exendin-4 (acetate) ≥95% |
Buy |
ChemScene CS-5100 | 5mg | $168 | Exendin-4acetate 99.44% |
Buy |
ChemScene CS-5100 | 10mg | $252 | Exendin-4acetate 99.44% |
Buy |
Exendin-4 (Acetate) Chemical Properties,Usage,Production
Description
Exendin-4 (48-86) amide is a 39-amino acid peptide fragment corresponding to residues 48-86 of exendin-4, a peptide produced in the salivary gland of the Gila monster, and an agonist of the glucagon-like peptide 1 receptor (GLP-1R; IC50 = 3.5 nM).1,2 Radiolabeled exendin-4 (48-86) amide localizes to the pancreas, kidneys, and bladder in a porcine model of diabetes induced by streptozotocin .3 Exendin-4 (48-86) amide (10 nmol/kg) improves motor performance in the rotarod test in an mouse model of Parkinson’s disease induced by MPTP.4 It reduces MPTP-induced loss of dopaminergic neurons in the substantia nigra in the same model. Formulations containing exendin-4 (48-86) amide have been used in the treatment of type 2 diabetes mellitus.References
1. Clardy, S.M., Mohan, J.F., Vinegoni, C., et al. Rapid, high efficiency isolation of pancreatic β-2. Doyle, M.E., Theodorakis, M.J., Holloway, H.W., et al. The importance of the nine-
3. Nalin, L., Selvaraju, R.K., Velikyan, I., et al. Positron emission tomography imaging of the glucagon-
4. Zhang, L., Zhang, L., Li, Y., et al. The novel dual GLP-
Preparation Products And Raw materials
Exendin-4 (Acetate) Suppliers
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+1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 | |
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18818260767 | sales@chemegen.com | China | 11289 | 58 |
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