Biological Activity
NIMA-related Kinase 7/never in mitosis A-related kinase 7 (NEK7) is essential to form procentriole. It participates in regulating the cell cycle. In addition to the pathological and physiological effects, NEK7 is also involved in the formation of the spindle during mitosis. It is expressed at a high level in gallbladder cancer. NEK7 controls cytokinesis and stability of the microtubule. It can activate the spindle assembly checkpoint. NEK7 might also be associated with hepatocellular carcinoma (HCC).
