Uses
Monoclonal Anti-Glucagon antibody produced in mouse has been used in immunofluorescence staining. The product may be used in several immunochemical techniques including immunohistochemistry and radioimmunoassay (RIA).
Uses
Monoclonal Anti-Glucagon antibody produced in mouse has been used:
- for the immunostaining of pancreatic tissue
- in flow cytometry and immunofluorescence imaging of pancreas cells
- for immunohistochemistry and morphology of pancreas
General Description
Glucagon is a 29 amino acid peptide hormone, which is produced by alpha cells of the pancreas. It is a hyperglycemic hormone. The gene is located on human chromosome 2q24.2.
Biochem/physiol Actions
Glucagon is critical in increasing blood sugar through glycogenolysis and increased gluconeogenesis. It regulates lipid and protein metabolism and modulates the fuel supply to all the organs. Glucagon plays a vital role in the modulation of postprandial hepatic glucose production. It is used to treat obesity. Elevated levels of glucagon are associated with glucagonoma and type 1 diabetes. It acts as a ligand to specific G-protein coupled receptor.
