4-(2-BroMoethoxy)-4'-hydroxybenzophenone

Chemical Properties

4-(2-BroMoethoxy)-4'-hydroxybenzophenone is White Solid

Uses

4-(2-BroMoethoxy)-4'-hydroxybenzophenone is used in the preparation of estrogen receptor modulators.

Preparation

Preparation by reaction of 4-hydroxybenzoic acid with b-bromophenetole, in solution of a polyphosphoric acid/85% phosphoric acid/zinc chloride mixture. The solution was heated to 50–60°, phosphorous trichloride was added during 1 h and the mixture heated for 20 h at 70° (74%).