Description
Phosphatidylinositol (PtdIns)-(3,5)-P2 (1,2-dipalmitoyl) (sodium salt) is a synthetic analog of natural PtdIns featuring saturated C16:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol stereochemistry as that of the natural compound. PtdIns-(3,5)-P2 is rapidly synthesized from PtdIns-(3)-P1 in yeast when a PtdIns-(3)-P5-hydroxy kinase is activated during hyperosmotic conditions.1 PtdIns-(3,5)-P2 is also present in mammalian cells, such as monkey COS-7 cells, where a similar biosynthetic route has been demonstrated.1WARNING This product is not for human or veterinary use.
References
[1] STEPHEN K. DOVE. Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis[J]. Nature, 1997, 390 6656: 187-192. DOI:
10.1038/36613
