(5α,12β,19α,20R)-2,3-Didehydro-16-methoxy-20-[[(7-methoxy-1,3-benzodioxol-5-yl)carbonyl]oxy]aspidospermidine-3-carboxylic acid methyl ester

Description

This second alkaloid obtained from the fruit of Alstonia venenata is the 3-methoxy derivative of the preceding base. It also forms colourless crystals from MeOH and has a specific rotation of [α] _D - 444.5° (c 0.3, CHC13). The ultraviolet spectrum in ethanolic solution has absorption maxima at 205, 252, 301 and 325 nm with a shoulder at 220 nm.

References

Majumder et at., Tetrahedron, 30, 2761 (1974)