Description
(Arg)
9 is a cationic cell-penetrating peptide.
1,2 It has been used to deliver various cargo to cells, including fluorescent proteins and plasmids. (Arg)
9 (5 and 10 μM) also protects primary rat cortical neurons from glutamate-induced excitotoxicity.
3
References
1. Chang, M., Chou, J.-C., and Lee, H.-J.
Cellular internalization of fluorescent proteins via arginine-rich intracellular delivery peptide in plant cells Plant Cell Physiol. 46(3),482-488(2005).
2. Lee, C.-Y., Li, J.-F., Liou, J.-S., et al.
A gene delivery system for human cells mediated by both a cell-penetrating peptide and a piggyBac transposase Biomaterials 32(26),6264-6276(2011).
3. Meloni, B.P., Brookes, L.M., Clark, V.W., et al.
Poly-arginine and arginine-rich peptides are neuroprotective in stroke models J. Cereb. Blood Flow Metab. 35(6),993-1004(2015).