Uses
Anti-Spectrin (α and β) antibody has been used in western blotting and immunostaining.
Uses
Anti-Spectrin antibody has been used in western blotting immunofluorescence and immunostaining.
General Description
Spectrin is the major cytoskeletal component in erythrocytes. It is composed of two types of polypeptides known as α and β with molecular weights of 240 and 220 kDa, respectively. The α- and β-chains form heterotetramers which are linked end-to-end via oligomeric actin and band 4.1 protein.
Biochem/physiol Actions
The spectrin-based membrane skeleton is essential to provide mechanical stability and membrane integrity. It is also responsible for protein organization, trafficking and resilience of erythrocytes.
