Description
An intermediate in the phase II reaction
that results in the formation of glucose conjugates of xenobiotics which contain substituents such as hydroxyl, amino or
sulfhydryl groups, the O-, N-, and S-glucosides, respectively.
UDPG is formed from uridine triphosphate and glucose-1-
phosphate in a reaction catalyzed by the enzyme UDPG pyro_x0002_phosphorylase. Glucoside formation is common in insects and
plants, whereas animals other than insects utilize uridine
diphosphate glucuronic acid to form glucuronides.