Application
Phenyltrans-styrene sulfone can be used as a pharmaceutical synthesis intermediate and can be used to prepare a cleaning solution for pre-cleaning thinning of flat glass substrates. By mass percentage, its components are: 1-20% potassium hydroxide, 1-15% alkanolamine, 5-35% sulfones and/or sulfoxides, 1-25% alcohols, 0.1-15% surfactant, and the remainder being water. The alkanolamine is one or more of monoethanolamine, triethanolamine, diethylene glycolamine, isopropanolamine, methyldiethanolamine, dimethylethanolamine, and hydroxyethylethylenediamine; the sulfones and/or sulfoxides include phenyltrans-styrene sulfone.
Synthesis
Phenyl TRANS-styryl sulfone was prepared as follows: in a vial, sulfonate 4 (1.5 eq.), Amberlyst 15 (140 mg), and graphene-copper(I) (5%) were dissolved in DMSO:EtOH 1:1. The vial was sealed and suspended in a Vortex system for 3 min at room temperature. Alkyne 2 (1 equiv) was added and the reaction was kept under continuous stirring at 100 C. After 24 h, the crude product of the reaction was filtered through an HPLC filter. The organic phase was dried over Na2SO4 and the solvent was removed under reduced pressure to give the desired products 5a-5q. (where 5a is phenyl TRANS-styryl sulfone).
