Description
Autocamtide 2 is a peptide substrate for calcium/calmodulin-dependent protein kinase (CaMK) and CaMKII.1,2 It is selectively phosphorylated by CaMK over bovine brain protein kinase C (PKC; Kms = 2 and >50 μM, respectively).1 Autocamtide 2 phosphorylation can be used to quantify CaMK and CaMKII activity.WARNING This product is not for human or veterinary use.
References
[1] P I HANSON. Expression of a multifunctional Ca2+/calmodulin-dependent protein kinase and mutational analysis of its autoregulation.[J]. Neuron, 1989, 3 1: 59-70. DOI:
10.1016/0896-6273(89)90115-3[2] R M WENHAM R A E M Landt. Glucose activates the multifunctional Ca2+/calmodulin-dependent protein kinase II in isolated rat pancreatic islets.[J]. The Journal of Biological Chemistry, 1994, 269 7: 4947-4952.
