Chemical Properties
white to light beige crystalline powder
Uses
Diglycolic acid was used in the preparation of needle-like aragonite particles from calcium nitrate aqueous solutions.
Definition
ChEBI: Diglycolic acid is a dicarboxylic acid.
General Description
Diglycolic acid is a toxic metabolite of diethylene glycol (DEG) responsible for DEG-induced proximal tubular necrosis.
Biochem/physiol Actions
Diglycolic acid has antithrombogenic properties and induces vasodilation. It inhibits succinate dehydrogenase activity in human proximal tubule cells.
Safety Profile
Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating vapors.
Purification Methods
Crystallise diglycolic acid from water. [Beilstein 3 IV 577.]