Description
C16 PEG Ceramide, MW 750 is used for liposome preparation with NMR studies and PEGylated lipoplexes preparation.
Uses
C16 PEG5000 Ceramide might be used to stabilize nanosized bilayer disks and in the preparation of lipid aggregates.
Uses
C16 PEG750 Ceramide might be used as a control to test for nonspecific interactions during titrations of DNA-nanotube complexes with polyethylene glycol (PEG)-conjugated lipids.
General Description
Ceramide is a sphingolipid metabolite. The ceramides differ in their acyl chain length.
Biochem/physiol Actions
Therapeutic drugs enclosed in poly-ethylene glycol (PEG) conjugated ceramide serves as liposomal carriers, ensuring a longer circulation period. It exhibits a neutral surface electrostatic charge which prevents the leakage of positively charged encapsulated drug molecule.
