Chemical Properties
storage temp. | -20°C |
form | buffered aqueous solution |
ANTI-LRP Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
Sigma-Aldrich SAB4200319 | 200μL | $520 | Anti-PTPRA antibody produced in rabbit ~1.0?mg/mL |
Buy |
Sigma-Aldrich SAB2501263 | 100μG | $568 | Anti-PPP2R4 (C-terminal) antibody produced in goat affinity isolated antibody, buffered aqueous solution |
Buy |
Sigma-Aldrich SAB2103654 | 100μL | $524 | Anti-MVP, (N-terminal) antibody produced in rabbit affinity isolated antibody |
Buy |
Sigma-Aldrich SAB1300081 | 100μG | $441 | Anti-LRP1 (C-term) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution |
Buy |
Sigma-Aldrich PRS2437 | 100μg | $524 | Anti-NOXA antibody produced in rabbit affinity isolated antibody, buffered aqueous solution |
Buy |
ANTI-LRP Chemical Properties,Usage,Production
Uses
Anti-LRP1 (N-terminal) antibody produced in rabbit has been used in immunoblotting and immunofluorescence.General Description
LDL receptor-related protein 1 (LRP1), also known as 2-macroglobulin receptor, is a large endocytic receptor, widely expressed on the surface and intracellular membranes of various cells. LRP1 is encoded by the gene mapped to human chromosome 12q13.3. The encoded protein is a member of the LDL receptor family. LRP1 is synthesized in the endoplasmic reticulum as a single-chain 600 kDa type I transmembrane glycosylated precursor that is cleaved subsequently in the Golgi complex into two subunits of 515 kDa and 85 kDa. The 515 kDa N-terminal subunit remains attached to the membrane through noncovalent association with the smaller 85 kDa C-terminal subunit, which contains the transmembrane and cytoplasmic domains.Biochem/physiol Actions
LRP1 expression is essential for early embryonic development. LRP1 facilitates various biological processes including lipoprotein metabolism, proteinase regulation, lysosomal enzymes activation and entry of viruses and toxins into the cells. In addition, It also regulates cell signaling pathways, cell migration, and neurodevelopment. LRP1 has an ability to bind at least 30 different ligands such as lipoproteins, proteinases, proteinase-inhibitor complexes, extra cellular matrix (ECM) proteins and various intracellular proteins. It also binds to bacterial toxins and viruses.Preparation Products And Raw materials
ANTI-LRP Suppliers
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