H-Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu-OH

Uses

Neuropeptide W-23 (human) (NPW-23), the active form of Neuropeptide W, is an endogenous agonist of NPBW1 (GPR7) and NPBW2 (GPR8)[1].

in vivo

References

[1] Ji L, et al. Modulation of CaV1.2 calcium channel by neuropeptide W regulates vascular myogenic tone via G protein-coupled receptor 7. J Hypertens. 2015 Dec;33(12):2431-42. DOI:10.1097/HJH.0000000000000723
[2] Pate AT, et al. Neuropeptide W increases mean arterial pressure as a result of behavioral arousal. Am J Physiol Regul Integr Comp Physiol. 2013 Oct 1;305(7):R804-10. DOI:10.1152/ajpregu.00119.2013
[3] Naso T, et al. Central neuropeptide W has anorexigenic effect in rats. J Anim Physiol Anim Nutr (Berl). 2014 Apr;98(2):228-34. DOI:10.1111/jpn.12067