Acetamide, N-[1,2-dihydro-2-oxo-5-(trifluoromethyl)-3-pyridinyl]-

Uses

3-Acetylamino-2-hydroxy-5-(trifluoromethyl)pyridine is a ligand developed by the Jin-Quan Yu group to affect the meta-selective C-H functionalization of phenols and anilines, including heterocyclic variants of these arenes.

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: C-H Activation
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reagent type: ligand
reaction type: Cross Couplings