Description
Norfentanyl-d
5 (hydrochloride) (Item No. 15832) is intended for use as an internal standard for the quantification of norfentanyl by GC- or LC-mass spectrometry. Norfentanyl is a thermal degradant and major urinary metabolite of the opioid analgesic, fentanyl (Item Nos.
ISO60197 |
14719). This product is intended for forensic and research applications.
General Description
An internal standard suitable for norfentanyl testing of urine, blood, or hair samples or isotope dilution methods by GC/MS or LC/MS in applications such as pain prescription monitoring, clinical toxicology, urine drug testing, or forensic analysis. Norfentanyl is a major urinary metabolite of fentanyl, a potent synthetic analgesic sold under various trade names including Sublimaze, Duragesic
, Actiq
, and Fentora
.
References
[1] ANURADHA GARG. Forced degradation of fentanyl: Identification and analysis of impurities and degradants[J]. Journal of pharmaceutical and biomedical analysis, 2010, 53 3: Pages 325-334. DOI:
10.1016/j.jpba.2010.04.004[2] ALPHONSE POKLIS Ronald B. Urine concentrations of fentanyl and norfentanyl during application of Duragesic transdermal patches.[J]. Journal of analytical toxicology, 2004, 28 6: 422-425. DOI:
10.1093/jat/28.6.422