Uses
H-Pro-Val-OH is a deprotonation dipeptide containing proline, which can catalyze the Michael addition reaction of acetone to trans-β-nitrostyrene. H-Pro Val OH can also serve as a substrate for fibroblast enzymes and prolinase, and has potential applications in biochemical analysis[1][2][3][4].
References
[1] Harrison AG, et al. Fragmentation reactions of deprotonated peptides containing proline. The proline effect. J Mass Spectrom. 2005 Sep;40(9):1173-86. DOI:
10.1002/jms.891[2] Davie EA, et al. Asymmetric catalysis mediated by synthetic peptides. Chem Rev. 2007 Dec;107(12):5759-812. DOI:
10.1021/cr068377w[3] Uramatsu M, et al. Different effects of sulfur amino acids on prolidase and prolinase activity in normal and prolidase-deficient human erythrocytes. Clin Chim Acta. 2007 Jan;375(1-2):129-35. DOI:
10.1016/j.cca.2006.06.027[4] Myara I, et al. Determination of prolinase activity in plasma. Application to liver disease and its relation with prolidase activity. Clin Biochem. 1985 Aug;18(4):220-3. DOI:
10.1016/s0009-9120(85)80043-6
