Propargyl-PEG4-N3
- Product NamePropargyl-PEG4-N3
- CAS1192590-91-2
- CBNumberCB25478239
- MFC11H19N3O4
- MW257.29
- MDL NumberMFCD25956354
- MOL File1192590-91-2.mol
Propargyl-PEG4-N3 Chemical Properties,Usage,Production
Biological Activity
Azido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562Preparation Products And Raw materials
Propargyl-PEG4-N3 Suppliers
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