ANTI-CD49C

Uses

Anti-ITGA3 antibody has been used in western blotting and immunohistochemical analysis.

General Description

Integrin α3 (ITGA3) belongs to the integrin family. It is expressed in various parts of the developing kidney, like undifferentiated metanephric mesenchyme (MM), primary vesicles, S-shaped bodies and developing tubules. This gene is located on human chromosome 17q21.33.

Biochem/physiol Actions

Integrin α3 (ITGA3) plays a major role in renal development. It may also participate in nephrogenesis. Mutations in ITGA3 gene results in interstitial lung disease, nephrotic syndrome and epidermolysis bullosa (ILNEB syndrome).