Uses
16:0 Phosphatidylethanol (Peth)/(1,2-dipalmitoyl-
sn-glycero-3-phosphoethanol) may be used:
- as an internal standard in liquid chromatography?mass spectrometry (LC-MS) analysis of PEth in human whole blood
- as an internal standard to spike blood samples for in liquid chromatography high-resolution mass spectrometry (LC?HRMS) analysis
- as a standard in calibration curve generation and validation of ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-ESI-MS/MS)
General Description
Phosphatidylethanol (PEth) is a phospholipid, that is generated in the the presence of ethanol in cell membranes. PEths like PEth 16:0/18:1, PEth 18:1/18:1, and PEth 16:0/16:0 possesses a common phosphoethanol head. Two fatty acid chains of variable length and degree of saturation are bound to this head group.
Biochem/physiol Actions
Phosphatidylethanol can be used as a biomarker in blood for chronic alcohol use.
