N-Boc-N-bis(PEG1-OH)

Description

N-Boc-N-bis(PEG1-OH) is a small PEG linker compound with two terminal hydroxy groups and a Boc protected amino group. The hydroxy groups enable further derivatization or replacement with other reactive functional groups. Boc can be deprotected under acidic conditions.

Biological Activity

N-Boc-N-bis(PEG1-OH) is a PROTAC bridge that belongs to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker used in the synthesis of antibody drug conjugates (ADCs).

in vitro

target

Cleavable

PEGs

Alkyl/ether