Uses
NAP is a neuroprotective peptide. It can also be used in biological study of integrating network, sequence and functional features using machine learning approaches towards identification of novel Alzheimer genes.
Definition
ChEBI: Davunetide is an oligopeptide.
Biological Activity
Davunetide (NAPVSIPQ; NAP) is an eight amino acid peptide identified as the active component of activity-dependent neuroprotective protein (ADNP). It has been found to be neuro-protective at femtomolar concentrations in vitro against the neural toxicity of a wide range of compounds. Davunetide has been investigated for Parkinsonμs disease and schizophrenia and in clinical trials for Alzheimnerμs Disease, targeting microtubule-tau Interaction.
