Uses
Anti-CD3, T Cell antibody produced in rabbit has been used in:
- immunoblotting
- immunofluorescence staining
- immunohistochemistry
- immunohistochemical analysis
General Description
CD3 is a 20kDa glycoprotein expressed on surface of all human T lymphocytes. CD3 molecule is encoded by the gene mapped to human chromosome 11q23.3. The CD3 antigen is expressed during thymopoiesis. It is also present in the majority of T-CLL and T-lymphomas and in approximately 70% of T-ALL.
Biochem/physiol Actions
CD3 is a human cell surface glycoprotein complex involved in signal transduction following binding of antigen receptor.
