preparation
The synthesized ester (12.5ml) was taken into a round bottom flask (250ml), 50ml of absolute ethanol & 37.5ml of hydrazine hydrate was added in the flask. The ester, ethanol & hydrazine hydrate for the synthesis of hydrazide must be in following ratio: Ester: Absolute ethanol: Hydrazine hydrate 1 : 4 : 3 Then round bottom flask was covered with aluminium foil, placed on hot plate & allowed to stir it for almost 12-15 hrs. As the solid product appeared, reaction completion was checked by performing TLC using n-hexane, ethyl acetate & TLC cards & observed under UV lamp. After completion of reaction n-hexane was added. Solution filtered as needle like crystals appeared. Allowed it to dry & a shiny off white product was obtained that was hydrazide & product was calculated (79%).
Uses
Used in the stnthesis of fluorinated poly (1, 3, 4-oxadiazole-ether-imide). N-(3,5-dinitrobenzoyl)-N?-(4-fluorobenzoyl)-hydrazine with 4-Fluorobenzhydrazide as solvent in NMP.
