Description
Bencarbazone is a post-emergence herbicide. It has a moderate aqueous solubility. There are large knowledge gaps in the public domain regarding its environmental fate parameters. It has a low mammalian toxicity and would not be expected to bioaccumulate. It has a moderate toxicity to birds, fish, aquatic invertebrates and earthworms.
Uses
Bencarbazone is used in the preparation of heterocyclylthiobenzamides as herbicides.
Definition
ChEBI: Bencarbazone is a thiocarboxamide that is benzenecarbothioamide substituted by a fluoro, 4-methyl-5-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-1,2,4-triazol-1-yl, and (ethanesulfonyl)nitrilo groups at positions 3,4 and 6, respectively. It is a herbicide used for the post-emergent control of broad-leaved weeds in corn, cereals, and sugar cane. It has a role as a herbicide, an agrochemical and an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor. It is a sulfonamide, a member of triazoles, a thiocarboxamide and a member of monofluorobenzenes.
Production Methods
Bencarbazone is commercially produced through a synthetic process involving the assembly of a complex triazolone-based molecular structure. The synthesis typically starts with fluorinated aromatic intermediates, which are reacted with sulfonyl and thiocarbonyl-containing reagents to form the herbicidal active ingredient.
Mechanism of action
Protox inhibitor, absorbed by roots and foliage and translocated
