1-Ethynyl-1-cyclohexanol

Chemical Properties

Colorless liquid

Uses

1-Ethynyl-1-cyclohexanol (ECHO) can undergo acetylation in the presence of a catalytic amount of ruthenium chloride at room temperature. It can be used to synthesize novel organotellurium(IV) compounds with potent inhibitory activity towards Cathepsin B. The polymerization of ECHO by transition metal catalysts leads to the formation of poly(ECHO). It can also react with transition metal hydride complexes to form vinyl derivatives by inserting into the M-H bonds.

Uses

Stabilization of chlorinated organic compounds, intermediate, corrosion inhibitor for mineral acids, medicine (sedative).

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 3, p. 416, 1955
Synthetic Communications, 18, p. 131, 1988 DOI: 10.1080/00397918808077336

Flammability and Explosibility

Non flammable