Uses
Penicillide is a potential ACAT, Calpain, and Oxytocin Receptor inhibitor.Also, it is used in preparation of (Methyl)bicyclo[2.2.1]heptanecarboxylate (Methoxy)(oxo)dibenzo[b,g][1,5]dioxocinyl Ester derivatives (Penicillide analogs) and degenerate of their activity as inhibitors of cholesterol ester transfer protein.
Definition
ChEBI: AS-186a is a dibenzodioxocine that is 5H,7H-dibenzo[b,g][1,5]dioxocin-5-one substituted by a hydroxy group at position 11, a (1S)-1-hydroxy-3-methylbutyl group at position 3 and a methoxy and a methyl group at positions 4 and 9 respectively. It is isolated from the culture broth of Penicillium asperosporum and acts as an acyl-CoA:cholesterol acyltransferase inhibitor. It has a role as an EC 2.3.1.26 (sterol O-acyltransferase) inhibitor, an antimicrobial agent and a Penicillium metabolite. It is a member of phenols, an aromatic ether, a lactone, a secondary alcohol and a dibenzodioxocine.
