1-Palmitoyl-2-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]caproyl]-sn-glycero-3-phosphocholine

Uses

16:0-06:0 NBD PC I suitable for use:

• in the preparation of fluid phase fluorescent bilayers
• to prepare liposomes/small unilamellar vesicles (SUVs)
• as substrate in in vitro enzyme assay of lipoteichoic acid (LTA) synthase enzyme (LtaS) to determine the enzyme specificity

Biological Activity

16:0-06:0 NBD PC (1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine) acts as a potential fluorescent probe. It is used for the quantification of the soluble and membrane-bound phospholipase A2 (PLA2) activity. 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) derivatives are widely used as fluorescent analogs of native lipids in biological and model membranes to study a variety of processes.