Ethanone, 2,2-difluoro-1-(4-methoxyphenyl)- (9CI)

Preparation

Also obtained by treatment of butyl-[2,2-difluoro-1-(4-methoxyphenyl)-eth-(Z)-ylidene]amine with aqueous hydrochloric acid in acetonitrile
Also obtained by reaction of p-anisole magnesium bromide with ethyl 2,2-difluoroacetate in THF at 78° (36%)
Also obtained by treatment of 2,2-difluoro-1-(4-methoxyphenyl)vinyl benzoate with aqueous potassium hydroxide in THF at r.t. for 12 h (72%)
Also obtained by reaction of Selectfluor with 1-(4-morpholinyl)-1-(4-methoxy-phenyl)ethene in the presence of 4 molecular sieves in acetonitrile at 10° for 8 h (64%).