Description
PSMA-11, also known as DKFZ-?PSMA-?11, HBED-CC-PSMA or Psma-hbed-CC, is a ligand to make gallium Ga 68-labeled PSMA-11, which has potential use as a tracer for PSMA-expressing tumors during positron emission tomography (PET). Upon intravenous administration of gallium Ga 68-labeled PSMA-11, the Glu-urea-Lys(Ahx) moiety targets and binds to PSMA-expressing tumor cells. Upon internalization, PSMA-expressing tumor cells can be detected during PET imaging. PSMA, a tumor-associated antigen and type II transmembrane protein, is expressed on the membrane of prostatic epithelial cells and overexpressed on prostate tumor cells
Uses
PSMA-11 2,2,2-Trifluoroacetate is an acidic salt of PSMA-11(C136660). PSMA-11 is the prostate-specific membrane antigen (PSMA) that has received increased consideration during the past few years as an excellent target for both imaging and therapy of prostate cancer after many years of outstanding preclinical.
