H-Tyr-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2

Uses

[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat is a fragments 22-37 of rat calcitonin gene related peptide (CGRP), targeting CGRP receptor and adenylate cyclase. Calcitonin is mainly produced by thyroid C cells while CGRP is secreted and stored in the nervous system[1].

References

[1] Jia S, et al. Calcitonin gene-related peptide enhances osteogenic differentiation and recruitment of bone marrow mesenchymal stem cells in rats. Exp Ther Med. 2019 Aug;18(2):1039-1046. DOI:10.3892/etm.2019.7659
[2] Russell FA, et al. Calcitonin gene-related peptide: physiology and pathophysiology. Physiol Rev. 2014 Oct;94(4):1099-142. DOI:10.1152/physrev.00034.2013
[3] Heino P, et al. Binding of CGRP analogs and their effect on adenylate cyclase activity in porcine iris-ciliary body. J Ocul Pharmacol Ther. 1998 Dec;14(6):543-54. DOI:10.1089/jop.1998.14.543