4'-METHYLUMBELLIFERYL-2-ACETAMIDO-3,4,6-TRI-ACETYL-2-DEOXY-BETA-D-GLUCOPYRANOSIDE

Uses

4-Methyl-7-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]oxy]-2H-1-benzopyran-2-one is an intermediate in synthesizing 4-Methylumbelliferyl 2-Acetamido-2-deoxy-β-D-glucopyranoside (M334000). a Fluorogenic substrate used for the assay of b-Acetylglucosaminidase. A fluorogenic substrate used for the diagnosis of GM2 gangliosidoses in leukocytes. Genetic defects in human b-hexosaminidase isozymes (Hex A & Hex B) result in various clinical and biochemical types of GM2 gangliosidosis. They include Tay Sachs disease, Sandhoff disease and other forms.Fluorescence: max. Abs. l = 325nm, max. Em. l = 378nm