13(S)-HOTRE

Description

13(S)-HOTrE is the 15-lipoxygenase (15-LO) product of linolenic acid. It has been detected in cell membranes and as the cholesteryl ester associated with the lesions of atherosclerosis, and in the biomembranes of soybeans exposed to 15-LO.

Uses

13(S)-HOTrE is an ester product.

Definition

ChEBI: 13(S)-HOTrE is the (13S)-stereoisomer of HOTrE. It has a role as a mouse metabolite. It is a conjugate acid of a 13(S)-HOTrE(1-).

References

[1] JUTTA BELKNER . The oxygenation of cholesterol esters by the reticulocyte lipoxygenase[J]. FEBS Letters, 1991, 279 1: Pages 110-114. DOI: 10.1016/0014-5793(91)80263-3
[2] MAURO MACCARRONE. In vitro oxygenation of soybean biomembranes by lipoxygenase-2[J]. Biochimica et biophysica acta. Biomembranes, 1994, 1190 1: Pages 164-169. DOI: 10.1016/0005-2736(94)90046-9
[3] RACHEL E WALKER. Effects of inflammation and soluble epoxide hydrolase inhibition on oxylipin composition of very low-density lipoproteins in isolated perfused rat livers.[J]. ACS Applied Bio Materials, 2021: e14480. DOI: 10.14814/phy2.14480