Uses
Histone modifications are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function.CENPA S68ph
Synthesized peptide corresponding to residues within 1-140 of CENP A with phosphorylation S68 modification.
Phosphorylation of Ser68 eliminates the binding of CENP-A to the assembly factor HJURP, thus preventing the premature loading of CENP-A to the centromere prior to mitotic exit.