Uses
Palladium(II) Trifluoroacetate is a pallaium salt of Trifluoroacetic Acid (T786035), a solvent used in a variety of organic synthesis and chemical processes. Also used in the synthesis of anticancer agents as well as phospholipase D inhibitors.
reaction suitability
core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Cross Couplings
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: C-H Activation
Purification Methods
Suspend it in trifluoroacetic acid and evaporate it on a steam bath a couple of times. The residue is then dried in vacuum (40-80o) to give a brown powder. It is hygroscopic. [Stephenson et al. J Chem Soc 3632 1965, Trost & Metzner J Am Chem Soc 102 3572 1980.]
